Project Scheme

 The goal of this project is to elucidate the molecular recognition mechanisms of soft molecules that play important roles in biomolecules and supramolecules such as DNA and neurotransmission processes from the viewpoint of molecular interactions by a Japanese, German, and French molecular cluster research team. For example, molecular recognition in neurotransmission is called a "Lock and Key" mechanism, which is attributed to the complementarity in shape and charge of the receptor pocket and the neurotransmitter. However, both receptors and neurotransmitters are flexible molecules, not rigid like the real lock and key, and it is difficult to answer clearly why soft molecules can discriminate between molecules with such small differences in molecular structure. In this project, we will elucidate the molecular recognition mechanism of soft molecules by a joint research team from Japan, Germany, and France, which specializes in gas-phase spectroscopy, the most accurate method for studying intermolecular interactions. The Japanese, German, and French research teams are complementary in their research methods and targets, and the joint research will bring us novel ideas and achievements. In addition, each research team includes young researchers and graduate students, and by participating in international joint research, they can grow as internationally-minded researchers, and further international collaborations will continue to the next generation.